The Effect Of Working Period Of Farmers Using Pesticides On SGPT Levels

Authors

  • Muawanah Politeknik Muhammadiyah Makassar image/svg+xml
  • Nur Qadri Rasyid Teknologi Laboratorium Medis, Politeknik Muhammadiyah Makassar
  • Rahmawati Politeknik Muhammadiyah Makassar image/svg+xml
  • Nurhikmah Politeknik Muhammadiyah Makassar image/svg+xml

DOI:

https://doi.org/10.59485/jtemp.v6i2.158

Keywords:

Farmer, Pesticide, SGPT, hepar, Photometric Method

Abstract

To improve the quality and productivity of agricultural products, farmers use pesticides as chemicals that function to control the growth of pests, diseases, and weeds. Excessive use of pesticides can have health impacts, one of which is impaired liver function because pesticides will accumulate in the liver and cannot be broken down or excreted. This will trigger an increase in the number of free radicals and cause hepatocyte cell damage, as well as increase SGPT levels. SGPT is an enzyme normally found in liver cells, but when there is a disruption in liver cells, the enzyme is released into the bloodstream, causing levels to increase and become an indicator of liver dysfunction. This study aims to determine the effect  of the work period of farmers using pesticides on SGPT (Serum Glutamic Pyruvate Transaminase) levels. The examination method used is the Photometric method with Bio System BA 200 with a number of 20 samples. Based on the results of the research, it was found that from 20 samples of farmers using pesticides, SGPT levels were still within normal limits according to the reference value of SGPT levels (Male=42 U/L, Female=32 U/L). The results of the SPSS 23 statistical test with a linear regression test obtained a significant value of p (0.237) > α > (0.05) in the work period, so there was no difference in SGPT levels. Thus, it can be concluded that there is no significant effect between the work period of farmers using pesticides with SGPT levels.

Downloads

Download data is not yet available.

References

Dahlan A, Simanjuntak JP, Mustopa R, et al. Pesticide Exposure and Increased Liver Enzyme Activity among Suburban Horticultural. J Info Kesehat. 2023;21(4):886-895. doi:10.31965/infokes.Vol21Iss4.1183

Muawanah, Fatmawati A, Rasyid NQ, Pramudya D. Profil Kadar Asetil Kolinesterase Pada Petani Pengguna Pestisida Di Kabupaten Jeneponto Profile of Acetyl Cholinesterase Level In Farmers Using Pesticides In Jeneponto Regency. Lontara Ris. 2025;6(1):4-9.

Al-ghanim KA, Mahboob S, Vijayaraghavan P, Al-misned FA, Ock Y, Kim H jae. Sub-lethal effect of synthetic pyrethroid pesticide on metabolic enzymes and protein profile of non-target Zebra fish, Danio rerio. Saudi J Biol Sci. 2020;27(1):441-447. doi:10.1016/j.sjbs.2019.11.005

Oktaviani R, Pawenang ET, Artikel I. Risiko Gejala Keracunan Pestisida pada Petani Greenhouse. HIGEIA J. 2020;4(2):178-188.

Ipmawati PA, Setiani O, Darundiati YH. Analisis Faktor-faktor Resiko Mempengaruhi Tingkat Keracunan Pestisida Pada Petani Di Desa Jati Kabupaten Sawangan Kabupaten Magelang Jawa Tengah. J Kesehat Masy. 2016;4:427-435.

Zardosht K, Momayyezi M, Sefidkar R, Fallahzadeh H, Momayyezi M, Ebrahimi AA. The Relationship between Pesticide Exposure and Liver and Renal Enzyme Disorders in Adults Aged 35-70 : The Results of the First Phase of the Shahedieh Cohort Study. JEHSD. 2024;9(2).

Desimal I, Mukono J. The Effects of Organophosphate Pesticides Exposure To Liver Function and Cholinesterase Serum Activity Among Apple Growers Applying Pesticides. Indones J Public Heal. 2012;10(1):70-76.

Susanti, Firdayanti. Pengaruh Penggunaan Pestisida Terhadap Kadar SGOT (Serum Glutamic Oxaloacetic Transaminase) dan Kadar SGPT (Serum Glutamic Pyruvic Transaminase) Pada Petani Di Desa Epeea Kecamatan Abuki Kabupaten Konawe. 2016;I(1):17-22.

Zahrox IF, Hairuddin, Sofiana KD. Hubungan Paparan Pestisida dengan Kadar SGOT dan SGPT Petani di Desa Pakis Kabupaten Jember. J Kesehat Lingkung Indones. 2021;20(1):47-52.

Sillehu S, Ibrahim I. Identifikasi Aktivitas Penggunaan Pestisida kimia yang Berisiko pada Kesehatan Petani Hortikultura. J Jumantik. 2022;7(1):7-12. doi:10.30829/jumantik.v7i1.10332

Afriayani I, Suwondo NN, Suzana M, Hermansyah H. Efek Penyemprotan Pestisida terhadap Kadar SGOT san SGPT Pada Petani Di Desa Simpang Asam. J Anal Kesehat. 2023;11(1):54-60.

Amelia S, Putri MA, Ibnusina F. Karakteristik dan Pengetahuan Petani Cabai Merah terhadap Penggunaan Pestisida Kimia : Studi Kasus di Kecamatan Payakumbuh , Kabupaten Lima Puluh Kota , Indonesia The Characteristics and Knowledges of Red Chili Farmers on the Use of Chemical Pesticides : 2022;3(2):133-142.

Tsani RA, Setiani O, Dewanti NAY. Hubungan Riwayat Pajanan Pestisida dengan Gangguan Fungsi Hati Pada Petani Di Desa Sumberejo Kecamatan Ngablak Kabupaten Magelang. J Kesehat Masy. 2017;5(3):411-420.

Ramdan IM, Candra KP, Purwanto H. Factors Associated With Cholinesterase Level of Spraying Workers Using Paraquat Herbicide At Oil Palm Plantation In East Kalimantan , Indonesia. 2020;19(1):16-20.

Maretha NE, Awaliyah NI, Wieke SW, Santoso AP. Pengaruh lama Paparan Pestisida Terhadap Gangguan Fungsi Hati Pada Petani Di Dusun Paritan Desa Sudimoro Kecamatan Mengaluh Kabupaten Jombang. Natl Conf Ummah. Published online 2020.

Marisa, Fradisa L, Putri IC. Kadar Serum Glutamic Pyruvic Transaminase (SGPT) Pada Tikus Yang Terinhalasi Pestisida. J Kesehat Tambusai. 2023;4(2):1516-1523.

Published

2025-12-05

How to Cite

The Effect Of Working Period Of Farmers Using Pesticides On SGPT Levels. (2025). MEDIKA TRADA, 6(2), 134-139. https://doi.org/10.59485/jtemp.v6i2.158